Pilocarpus.

Pilocarpus jaborandi is a shrub native to Eastern Brazil, where Piso (511), of Holland, 1643, first mentions its use as a modifier of the infusion of ipecac. Plumier, 1693, also (515) refers to the mixture, describing two varieties of jaborandi. Its conspicuous introduction to medicine occurred in 1874, when Dr. Coutinho (170), of Pernambuco, from observing its native uses, made its qualities as a sialogogue known to the medical world. The plant has been cultivated in European greenhouses since the middle of the last century, but no "scientific" observer gave it the honor of a thought in therapeutic directions.

The History of the Vegetable Drugs of the U.S.P., 1911, was written by John Uri Lloyd.