Extractum Euonymi Br. Extract of Euonymus.
Related entries: Euonymus
Dry Extract of Euonymus; Extract of Wahoo; Extrait d'Evonymus atropurpureus, Fr. Cod.; Extrait de Fusain Americaine, Fr.; Spindelbaumextrakt, Spillbaumrindenextrakt, G.
"Exhaust Euonymus Bark in No. 20 powder with Alcohol (45 per cent.) by the percolation process. Evaporate the percolate and thoroughly dry the residue. Powder the product as far as possible and mix it with one-fourth of its weight of Calcium Phosphate, continuing the drying and powdering until a sufficiently dry preparation is obtained; transfer this to a well-closed bottle." Br.
This extract was not admitted to the U. S. P. IX, but was retained in the Br. Pharm. (1914) and introduced into the National Formulary IV which directs the percolation of euonymus in No. 40 powder with alcohol 4 volumes and water 1 volume. The percolate is evaporated or distilled and the residue dried and mixed with dried starch so that 1 Gm. of the extract represents 4 Gm. of euonymus. On account of the reports of physicians of cumulative effects the following note was inserted:
"CAUTION—It has been stated that the absorption of Euonymus in the gastro-intestinal tract is uncertain and irregular. To avoid an accumulation of the drug or toxic action, the physician should carefully guard the dosage and determine in each case the tolerance of the patient." N. F. IV. Dry and powdered extract of euonymus is frequently but erroneously termed "euonymin."
Dose, one to three grains (0.065 to 0.2 Gm.).