Tinctura Jalapae. Br. Tincture of Jalap. -- Tinctura Jalapae Composita. Compound Tincture of Jalap.
Related entries: Jalap
Teinture (alcoole) de Jalap, Fr. Cod.; Jalapentinktur, G.
"Jalap, in No. 40 powder, 200 grammes; Alcohol (70 per cent.), a sufficient quantity. Moisten the powder with one hundred millilitres of the Alcohol; pack in a percolator; gradually add more of the Alcohol until six hundred millilitres of percolate have been collected; press the marc; add the expressed liquid to the percolate; set aside for twenty-four hours; filter. Determine the amount of Jalap Resin present in ten millilitres of the strong tincture so prepared by the process described under 'Jalapae Resina' and dilute the remainder of the strong tincture with sufficient of the Alcohol to produce a Tincture of Jalap containing 1.5 grammes of the Resin in 100 millilitres. When 10 millilitres of the Tincture, concentrated by evaporation, are mixed with eight times their volume of water, the resin thus separated, washed with water and dried at a gentle heat, weighs not less than 0.145 or more than 0.155 gramme." Br.
This tincture is no longer official in the U. S. Pharmacopoeia, but is in the N. F. IV (see Part III). The tincture of jalap of the U. S. P. 1870 was made by percolating six troy-ounces of powdered jalap with a mixture of two measures of alcohol and one of water, until two pints of tincture were obtained.
This tincture is now prepared on the basis of proportion of resin, not of crude drug, as formerly. It possesses the medicinal virtues of jalap, and is sometimes added to cathartic mixtures.
Dose, one-half to one fluidrachm (1.8-3.75 mils).
Tinctura Jalapae Composita. Br.
Compound Tincture of Jalap.
"Jalap, in No. 40 powder, 80 grammes; Scammony Resin, in powder, 15 grammes; Turpeth, in No. 40 powder, 10 grammes; Alcohol (60 per cent.), sufficient to produce 1000 millilitres. Moisten the mixed powders with one hundred millilitres of the Alcohol, and complete the percolation process." Br.
This tincture is also official in the N. V. IV. It is a harsh but active purgative, capable of producing serious effects if given in over-dose.
Dose, one-half to one fluidrachm (1.8-3.75 mils).